Scientific Challenge: proposal accepted!

BioSolveIT’s scientific challenge ‘fall 2016’

biosolve

Dear Natalia Sizochenko,
Congratulations!
Your proposal ‘The mosquito-borne viruses: The design of antivitial drugs’ was selected to be among the 5 to enter BioSolveIT’s scientific challenge ‘fall 2016’. We are excited to see so many ambitious academic projects on the start!

 

scientific challenge

BioSolveIT is inviting academic teams, non-profit organizations and individuals to participate in an exciting Scientific Challenge: if you are working on a drug discovery problem, take advantage of BioSolveIT’s wide array of software tools to meet your goals. How to participate? Just send us a proposal for the project you’d like to advance using BioSolveIT software. We will review every proposal very carefully and award the 5 most attractive ones. A new contest starts every three months.

In a first phase, the most promising 5 proposals will receive free BioSolveIT licenses for 3 months to con­duct the desired research. For phase II, the most interesting 3 results are granted a free license extension by 9 months and we will sponsor the presentation of the overall best achievement with a travel grant of 1000€. For more details please read the terms of challenge.

The mosquito-borne viruses: The design of antivirial drugs
Mosquito-borne viruses of Flaviviridae virus family (West Nile virus, Zika virus, Yellow fever virus) are                  dangerous for human. In some cases  toxic phases could be a fatal for human. Usually, antiviral drugs, as well as treatment with interferons, do not have a positive effect on patients. The aim of  proposed project is screening of drug database in order to find suitable drug. Quantitative models for these drugs could be useful for the purpose of development of lead drugs. Using a SolveIT software we are going to analyze a series of drugs by means of molecular docking (FlexX), QSAR analysis (SeeSAR) and similarity search (FTrees). Results of simulations  would be used to create guidelines of designing of potential drugs.